Chemometric Assisted Spectrophotometric Methods for Simultaneous Determination of Paracetamol and Tolperisone Hydrochloride in Pharmaceutical Dosage Form
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منابع مشابه
Titrimetric and Spectrophotometric Methods for the Determination of β-blockers in Pharmaceutical Dosage Form
Three new methods using titrimetric and spectrophotometry are described for the determination of Propranolol Hydrochloride (PPH) and Atenolol (AN) with potassium bromate as the oxidimetric reagent and acid dyes, Methyl orange and Indigo carmine. In direct titrimetric (method A), the drug is titrated directly with bromate in acid medium and in the presence of excess of bromide using methyl orang...
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Two methods for simultaneous estimation of Paracetamol and Tolperisone Hydrochloride in combined tablet dosage form have been developed using Water as a solvent. The first UV spectrophotometric method was a determination using the simultaneous equation method at 242.5 nm and 260 nm. The second UV spectrophotometric method is the Q – analysis (absorption ratio) method, which involves the formati...
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Diclofenac sodium is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. Tolperisone hydrochloride is a piperidine derivative, is a centrally-acting muscle relaxant. Two simple, accurate and economic methods; Q analysis and first order derivative method have been described for the simultaneous spectrophotometric es...
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A new method was established for simultaneous estimation of Tolperisone and Diclofenac sodium by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Tolperisone and Diclofenac sodium by using Agilent C18 column flow rate was 1ml/min, mobile phase ratio was (70:30 v/v) ACN: phosphate buffer pH 3 (pH was adjusted with orthophosphoricacid), detection wa...
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Spectrophotometric techniques were developed for the determination of single and binarymixture Promethazine hydrochloride (PMH) and Paracetamol (PCM). Normal and first derivative (D) used for single drug at λ 249.5 and 243.0 for PMH and 243.5 and 225 for PCM. The simultaneous determination of binary mixture (PMH) and (PCM) were accomplished by first derivative (D) and second derivative (D) spec...
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ژورنال
عنوان ژورنال: Eurasian Journal of Analytical Chemistry
سال: 2016
ISSN: 1306-3057
DOI: 10.12973/ejac.2017.00164a